IN VITRO DYNAMIC BLOOD TESTING
Acels Medical specializes in medical device benchtop testing. Our custom test method development and in-house specialized testing equipment enable us to perform a range of biological, physical, and performance tests that comply with applicable regulatory standards.
In vitro dynamic blood circuits are an essential test method for biomedical devices that interact with the circulatory system. The Acels team has expertise in blood gas exchange testing and dynamic blood hemolysis testing, as well as a range of other performance assessments suitable for evaluating cardiovascular and pulmonary medical devices.
In Vitro Gas Exchange
Blood gas exchange testing evaluates the gas transfer efficiency of blood oxygenators, ECMO, or ECCO2R devices at various gas and blood flow rates. Our laboratory is equipped with advanced blood and gas flow analysis equipment, enabling the monitoring of key parameters in compliance with ISO and FDA regulations. The test setup can be modified to meet specific testing goals.
In Vitro Hemolysis
In vitro hemolysis testing is required for medical devices designed to interact with the circulatory system, whether internally or externally. Benchtop in vitro hemolysis testing provides valuable insights into the physical and material aspects of device design. Under normal operating conditions, such as specified flow rates and pressures, blood parameters are monitored over time to evaluate the blood’s response to device exposure.
Other Test Circuits
Test circuits can be customized to evaluate various performance characteristics, such as the stability of biocompatible coatings or physical properties like pressure-flow relationships.
Biocompatibility Testing
In Vitro Human Cell Viability
Our team is experienced in specialized MTT assays to evaluate human cell viability. The MTT assay is a gold-standard method for assessing the cytotoxicity and biocompatibility of materials, medical devices, and compounds.
In Vitro Materials Hemolysis
We perform in vitro hemolysis testing using a direct contact method to evaluate the blood compatibility of materials used in medical devices, implants, and other healthcare products. Hemolysis testing is essential to ensure that materials do not cause the destruction of red blood cells, which could lead to adverse reactions in patients.
Biomaterials Interaction
Biomaterials Interaction
Biomaterials Interaction
We perform a range of biomaterials interaction tests to evaluate material and surface coating performance, including:
- Protein adhesion studies
- Blood clotting and thrombin deactivation
- Complement activation assays
Custom Test Development
Biomaterials Interaction
Biomaterials Interaction
Our team specializes in custom test protocol development for evaluation of medical device materials and surface coatings. Testing is conducted in accordance with ISO 10993 and other relevant international standards.
Interested in collaborating on a project?